[Balanor]

But buy a really expensive and really surefire poison like Dragon Bile and you'll never use it, simply out of fear of whiffing your first round of attacks (since the tougher baddies who deserve to get Dragon-Biled usually have the better Armor Classes) and wasting hundreds or thousands of Talons.

It's been some time since I tested the poisons as I was modifying how they worked, but this should not be a concern. The weapon remains poisoned until it actually hits a target. So even if you miss your first round of attacks, your weapon should still remain poisoned.

Again though, I am not 100% sure on this - so if you have confirmed that poison does actually get removed from the weapon on an unsuccessful attack, then that is the way it works. :)